Mark P Mattson Selected Research

Apolipoproteins

1/2020	Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
1/2019	A Novel Apolipoprotein E Antagonist Functionally Blocks Apolipoprotein E Interaction With N-terminal Amyloid Precursor Protein, Reduces β-Amyloid-Associated Pathology, and Improves Cognition.
5/2008	Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells.
6/2007	Calcium and neurodegeneration.
7/2006	Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.

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Mark P Mattson Research Topics

Disease

105	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2002
59	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 01/2002
36	Stroke (Strokes) 04/2019 - 02/2002
28	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2002
23	Ischemic Stroke 01/2019 - 06/2006
20	Neoplasms (Cancer) 01/2019 - 01/2002
16	Inflammation (Inflammations) 02/2024 - 03/2007
16	Nervous System Diseases (Neurological Disorders) 01/2021 - 03/2003
16	Ischemia 01/2019 - 04/2002
15	Cognitive Dysfunction 01/2020 - 02/2004
15	Insulin Resistance 01/2020 - 04/2002
14	Huntington Disease (Huntington's Disease) 01/2023 - 01/2003
10	Neuroblastoma 01/2021 - 09/2005
10	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2002
10	Obesity 10/2019 - 06/2003
10	Brain Ischemia (Cerebral Ischemia) 06/2018 - 07/2002
10	Body Weight (Weight, Body) 05/2017 - 05/2003
9	Brain Injuries (Brain Injury) 01/2021 - 12/2002
9	Dementia (Dementias) 12/2018 - 10/2002
8	Amyloid Plaque 01/2021 - 12/2002
8	Type 2 Diabetes Mellitus (MODY) 04/2019 - 09/2002
8	Neuroinflammatory Diseases 01/2019 - 07/2007
8	Hypoxia (Hypoxemia) 06/2018 - 04/2002
8	Infarction (Infarctions) 05/2013 - 04/2002
7	Infections 08/2015 - 10/2002
7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2012 - 10/2002
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 10/2003
5	Seizures (Absence Seizure) 01/2023 - 12/2002
5	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2018 - 07/2002
5	Weight Loss (Weight Reduction) 08/2015 - 05/2002
5	Wounds and Injuries (Trauma) 03/2013 - 01/2003
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2019 - 10/2009
4	Atrophy 11/2017 - 12/2011
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 11/2015 - 07/2007
4	Disease Progression 11/2012 - 03/2003
3	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2006
3	Ketosis 01/2022 - 01/2018
3	Weight Gain 01/2022 - 05/2014
3	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 11/2009
3	Premature Aging 11/2019 - 11/2014
3	Hyperglycemia 01/2017 - 03/2003
3	Iron Deficiencies 12/2016 - 09/2008

Drug/Important Bio-Agent (IBA)

54	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2002
39	Amyloid (Amyloid Fibrils)IBA 01/2021 - 03/2002
27	Amyloid beta-PeptidesIBA 01/2021 - 01/2002
26	Peptides (Polypeptides)IBA 01/2019 - 06/2002
23	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 04/2002
21	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 05/2002
17	CalciumIBA 01/2020 - 01/2002
14	EnzymesIBA 01/2019 - 10/2003
13	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 11/2002
13	CytokinesIBA 01/2015 - 12/2004
11	Presenilin-1IBA 01/2021 - 05/2002
9	Insulin (Novolin)FDA Link 02/2024 - 06/2003
9	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2021 - 06/2006
9	HomocysteineIBA 03/2012 - 01/2002
9	Folic Acid (Vitamin M)FDA LinkGeneric 07/2005 - 01/2002
8	LipidsIBA 01/2023 - 02/2004
8	SynucleinsIBA 01/2019 - 06/2011
7	LeptinIBA 02/2024 - 06/2003
7	Amino Acids FDA Link 01/2023 - 01/2003
7	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 08/2007
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 01/2002
7	PresenilinsIBA 06/2007 - 01/2002
6	polyglutamineIBA 01/2023 - 01/2003
6	Hormones (Hormone)IBA 01/2020 - 05/2010
6	NAD (NADH)IBA 10/2019 - 01/2009
6	Glucagon-Like Peptide 1 (GLP 1)IBA 04/2019 - 09/2002
6	Protein Isoforms (Isoforms)IBA 01/2019 - 01/2002
6	Transcription Factors (Transcription Factor)IBA 05/2017 - 09/2003
6	IronIBA 12/2016 - 12/2004
5	Adenosine Triphosphate (ATP)IBA 01/2021 - 04/2002
5	ApolipoproteinsIBA 01/2020 - 07/2006
5	AntioxidantsIBA 11/2015 - 01/2007
5	Glutamic Acid (Glutamate)FDA Link 08/2011 - 07/2002
5	Nerve Growth Factors (Neurotrophins)IBA 02/2011 - 12/2004
5	Glucagon-Like Peptide-1 ReceptorIBA 01/2011 - 01/2009
4	Sirtuin 3IBA 01/2023 - 01/2016
4	Complement System Proteins (Complement)IBA 01/2021 - 08/2007
4	Apolipoprotein E4IBA 01/2020 - 07/2002
4	KetonesIBA 01/2020 - 06/2013
4	Uric Acid (Urate)IBA 01/2019 - 01/2007
4	CarbonIBA 01/2019 - 03/2002
4	Intravenous Immunoglobulins (IVIG)FDA Link 01/2018 - 08/2007
4	PhytochemicalsIBA 09/2016 - 08/2007
4	UbiquitinIBA 04/2012 - 03/2004
4	CeramidesIBA 08/2010 - 10/2002
4	Superoxide Dismutase-1IBA 04/2010 - 03/2004
4	Blood Glucose (Blood Sugar)IBA 02/2009 - 09/2002
3	KATP ChannelsIBA 01/2021 - 04/2002
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2012
3	IncretinsIBA 04/2019 - 06/2010
3	Exenatide (Byetta)FDA Link 01/2019 - 02/2009
3	A-Form DNA (A-DNA)IBA 01/2018 - 10/2014
3	EstersIBA 01/2017 - 08/2003
3	Free RadicalsIBA 01/2017 - 10/2009

Therapy/Procedure

14	Therapeutics 01/2022 - 04/2002
11	Diet Therapy (Therapy, Diet) 09/2013 - 04/2002
8	Caloric Restriction 01/2017 - 02/2003
4	Drug Therapy (Chemotherapy) 01/2022 - 12/2002